CNS
General
Anesthetics
A. The student
shall be able to describe the stages of general anesthesia, theories of action
of anesthesia, and factors governing the approach to steady state.
B. The student
shall know the applications for specific anesthesia, the mechanism of action
and end organ effects, the side effects, advantages and disadvantages for
nitrous oxide, halothane, methoxyflurane, enflurane, isoflurane, desflurane,
sevoflurane, droperidol-fentanyl, and Ketamine, thiopental, etomidate, and
C. The student
shall recognize the role of various injectable (intravenous) anesthetics.
Local
Anesthetics
A. The student
shall be able to describe the pharmacokinetics, sites of action, neurons
affected, mechanism of actions of local anesthetics.
B. The student
shall note the reactions of local anesthetics in solutions, as well as the
unique attributes of various medications in the class.
Antipsychotic
Drugs
A. The student
shall be able to describe the role of dopamine in schizophrenia.
B. The student
shall be able to recognize the mechanism and sites of action of antipsychotic
drugs.
C. The student
shall demonstrate the therapeutic effects, side effects, and drug interactions
of chlorpromazine, thioxanthenes, butyrophenones, clozapines, risperidone,
quetapine, and olanzapine.
D. The student
shall be able to describe neurologic adverse effects of antipsychotic drugs.
Drugs for
Parkinson’s Disease
A. The student
shall be able to describe the underlying causes of Parkinson’s Disease.
B. The student
shall be able to understand the chemistry, mechanism of action, administration
routes, side effects, duration of effect, therapeutic uses and preparations of
L-DOPA, Carbidopa, amantidine, trihexphenidyl and benztropine, bromocriptine,
pergolide, pramipexole and ropinirole, tolcapone, and selegiline.
Antidepressants
A. The student
shall recognize the chemistry, effects and mechanisms, pharmacokinetics, side
effects and toxic effects, and drug interactions of various generations of
tricyclic antidepressants.
B. The student
shall recognize the chemistry, effects and mechanisms, pharmacokinetics, side
effects and toxic effects, and drug interactions of serotonin uptake
inhibitors.
C. The student
shall recognize the chemistry, effects and mechanisms, pharmacokinetics, side
effects and toxic effects, and drug interactions of monoamine oxidase
inhibitors and dopamine uptake inhibitors.
D. The student
shall appreciate the differences in cost for various anti-depressants.
Lithium and
Antianxiety - Sedative-hypnotic drugs
A. Student shall
be able to describe the mechanism, pharmacology, toxicity, therapeutic uses,
side effects, and drug-drug interactions of lithium.
B. The student
shall be able to describe the importance, distribution, synthesis, mechanism of
action, and breakdown of GABA.
C. The student
shall be able to describe the chemistry, kinetics, mechanism of action,
pharmacological effects, adverse effects, and uses of sedative-hypnotic
medications such as barbiturates, benzodiazepines, buspirone, and zolpidem.
Antiseizure
Drugs
A. The student
shall be able to show understanding of the pathophysiology and classification
of seizures and the general principles behind antiepileptics and theire
selection for specific seizure treatment.
B. The student
shall be able to describe the mechanism of actions, therapeutic uses,
pharmacokinetics, drug interactions, and undesired effects of phenytoin-like
medications, carbamazepine, phenobarbitol, primidone, gabapentin, lamotrigene,
topiramate, tiagabine, valproic acid, ethosuximide, and benzodiazepams.
Narcotic
Analgesics
A. The student
shall be able to demonstrate knowledge of the source, structure, receptor
interaction, mechanism of action, major pharmacologic actions, side effects,
precautions and drug interactions of morphine and related drugs.
B. The student
shall be able to distinguish the unique attributes of meperidine and related
drugs, methadone and related drugs, agonists-antagonists and partial agonists,
and narcotic antagonists, and dextromethorphan.
Drug of Abuse
A. The student
shall be able to differentiate between drug tolerance, dependence and
addiction.
B.
The student shall be able to describe the physiological effects, tolerance and
withdrawal patterns and medical uses of the following drug classes: opiods,
barbituates and related sedatives, alcohol, psychedelics, psychomotor
stimulants, and cannaboids
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